ABSTRACT
@#Objective To investigate the association between physical activity and glucose metabolism during the second trimester of pregnancy． Methods A cross－sectional study was conducted from March 2017 to November 2018． 1 083 pregnant women at 20－28 weeks of gestation in Guangzhou，China were recruited into this study． A standardized questionnaire was used to collect demographics and lifestyles． Physical activity was assessed by the international physical activity questionnaire． The participants underwent an oral glucose tolerance test． Multiple linear regression was used to analyze the association between physical activity and blood glucose． Logistic regression analysis model was used to analyze the association between physical activity and gestational diabetes mellitus(GDM) ． Results Only 36. 57% of pregnant women met the recommended level of total physical activity． There was a negative correlation ( β= －0. 104， P= 0. 017) between total physical activity and postprandial 2 h blood glucose． Results from different types of physical activities showed that the recreation，sport，and leisure－time physical activity were negatively associated with postprandial 1 h blood glucose ( β = －0. 114，P = 0. 042) ． No significant association was found between either various types of physical activities or sedentary time and GDM． Conclusions Physical activity during mid－pregnancy is inadequate in pregnant women in Guangzhou，China． Higher total physical activity and recreation，sport，and leisure－time physical activity in the second trimester of pregnancy are associated with lower postprandial blood glucose.